Diverse RNA granules have been intensely researched. Yet, fundamental questions remain unaddressed:
- Which mRNAs enrich in RNA granules?
- How do mRNAs become enriched in RNA granules?
- How do mRNAs influence granule assembly?
- What happens to the mRNAs once they arrive in RNA granules?
- How are mRNAs regulated in RNA granules?
- How do granule-enriched mRNAs shape the biology of a cell?
- How do granule mRNAs become miss-regulated to drive disease?